anti- HOPX antibody

anti- HOPX antibody

Product Name

HOPX antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Atypical homeodomain protein which does not bind DNA and is required to modulate cardiac growth and development. Acts via its interaction with SRF, thereby modulating the expression of SRF-dependent cardiac-specific genes and cardiac development. Prevents SRF-dependent transcription either by inhibiting SRF binding to DNA or by recruiting histone deacetylase(HDAC) proteins that prevent transcription by SRF. Overexpression causes cardiac hypertrophy(By similarity). May act as a tumor suppressor.

IMMUNOGEN INFORMATION

Immunogen

HOP homeobox

Synonyms

HOD, HOP, LAGY, NECC1, OB1

Observed MW

8-12kd

APPLICATION

Tested Application

ELISA, IF, WB

Recommended Dilution

WB: 1:500-1:2000; IF: 1:50-1:200

UNIPROT INFORMATION

UniProt ID

Q9BPY8

IMAGES

mouse brain were subjected to SDS PAGE followed by western blot with FNab03970(HPOX antibody) at dilution of 1:1000