anti- HPS4 antibody

anti- HPS4 antibody

Product Name

HPS4 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Component of the BLOC-3 complex, a complex that acts as a guanine exchange factor(GEF) for RAB32 and RAB38, promotes the exchange of GDP to GTP, converting them from an inactive GDP-bound form into an active GTP-bound form. The BLOC-3 complex plays an important role in the control of melanin production and melanosome biogenesis and promotes the membrane localization of RAB32 and RAB38(PubMed:23084991).

IMMUNOGEN INFORMATION

Immunogen

Hermansky-Pudlak syndrome 4

Synonyms

KIAA1667

Observed MW

70 kDa and 90 kDa

APPLICATION

Tested Application

ELISA, WB, IF, IP, IHC

Recommended Dilution

WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

Q9NQG7

IMAGES

Immunohistochemistry of paraffin-embedded human liver tissue slide using FNab04000(HPS4 Antibody) at dilution of 1:50

IP result of anti-HPS4 (FNab04000 for IP and Detection) with HeLa cell lysate.

A375 cells were subjected to SDS PAGE followed by western blot with FNab04000(HPS4 antibody) at dilution of 1:200