anti- HSD17B6 antibody

anti- HSD17B6 antibody

Product Name

HSD17B6 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

NAD-dependent oxidoreductase with broad substrate specificity that shows both oxidative and reductive activity(in vitro). Has 17-beta-hydroxysteroid dehydrogenase activity towards various steroids(in vitro). Converts 5-alpha-androstan-3-alpha,17-beta-diol to androsterone and estradiol to estrone(in vitro). Has 3-alpha-hydroxysteroid dehydrogenase activity towards androsterone(in vitro). Has retinol dehydrogenase activity towards all-trans-retinol(in vitro). Can convert androsterone to epi-androsterone. Androsterone is first oxidized to 5-alpha-androstane-3,17-dione and then reduced to epi-andosterone. Can act on both C-19 and C-21 3-alpha-hydroxysteroids.

IMMUNOGEN INFORMATION

Immunogen

hydroxysteroid(17-beta) dehydrogenase 6 homolog(Mouse)

Synonyms

RODH, SDR9C6

Observed MW

33-35kd

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:500-1:2000; IHC: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

O14756

IMAGES

Immunohistochemistry of paraffin-embedded human lung cancer using FNab04027(HSD17B6 antibody) at dilution of 1:50

human liver tissue were subjected to SDS PAGE followed by western blot with FNab04027(HSD17B6 antibody) at dilution of 1:200