anti- HSP47 antibody

anti- HSP47 antibody

Product Name

HSP47 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

BACKGROUND

This gene encodes a member of the serpin superfamily of serine proteinase inhibitors. The encoded protein is localized to the endoplasmic reticulum and plays a role in collagen biosynthesis as a collagen-specific molecular chaperone. Autoantibodies to the encoded protein have been found in patients with rheumatoid arthritis. Expression of this gene may be a marker for cancer, and nucleotide polymorphisms in this gene may be associated with preterm birth caused by preterm premature rupture of membranes. Alternatively spliced transcript variants have been observed for this gene, and a pseudogene of this gene is located on the short arm of chromosome 9.

IMMUNOGEN INFORMATION

Immunogen

serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)

Synonyms

47 kDa heat shock protein, AsTP3, CBP1, CBP2, Collagen binding protein, Colligin, gp46, HSP47, PIG14, PPROM, RA A47, Serpin H1, SERPINH1, SERPINH2

Observed MW

Refer to figures

APPLICATION

Tested Application

ELISA, IHC, WB, IF

Recommended Dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200

UNIPROT INFORMATION

UniProt ID

P50454

IMAGES

Immunohistochemistry of paraffin-embedded human hepatocirrhosis tissue slide using FNab04045( SERPINH1 Antibody) at dilution of 1:50

Immunofluorescent analysis of HeLa cells using FNab04045( SERPINH1 Antibody) at dilution of 1:25 and Alexa Fluor 488-conjugated Goat Anti-Rabbit IgG(H+L)

HT-1080 cells were subjected to SDS PAGE followed by western blot with FNab04045(SERPINH1 antibody) at dilution of 1:1000