anti- HTRA2 antibody

anti- HTRA2 antibody

Product Name

HTRA2 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Serine protease that shows proteolytic activity against a non-specific substrate beta-casein. Promotes or induces cell death either by direct binding to and inhibition of BIRC proteins(also called inhibitor of apoptosis proteins, IAPs), leading to an increase in caspase activity, or by a BIRC inhibition-independent, caspase-independent and serine protease activity-dependent mechanism. Cleaves THAP5 and promotes its degradation during apoptosis. Isoform 2 seems to be proteolytically inactive.

IMMUNOGEN INFORMATION

Immunogen

HtrA serine peptidase 2

Synonyms

HtrA serine peptidase 2, HTRA2, OMI, PARK13, PRSS25, Serine protease 25, Serine proteinase OMI

Observed MW

36 kDa

APPLICATION

Tested Application

ELISA, WB, IHC, IP

Recommended Dilution

WB: 1:500-1:2000; IP: 1:500-1:1000; IHC: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

O43464

IMAGES

Immunohistochemistry of paraffin-embedded human kidney using FNab04070(HTRA2 antibody) at dilution of 1:100

IP Result of anti-HTRA2 (IP:FNab04070, 4ug; Detection:FNab04070 1:500) with Raji cells lysate 2000ug.

HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab04070(HTRA2 antibody) at dilution of 1:2000