anti- ICAM-1 antibody

anti- ICAM-1 antibody

Product Name

ICAM-1 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

ICAM-1(CD54) is a 90-kDa transmembrane glycoprotein of the immunoglobulin superfamily and is critical for the firm attachment and transmigration of leukocytes out of blood vessels and into tissues(PMID: 19307690). ICAM-1 is expressed by several cell types, typically on endothelial cells and cells of the immune system, and its expression can be up-regulated by various stimuli, including TNF-α, INF-γ, IL-1 and thrombin(PMID: 3086451; 9694714; 15979056).

IMMUNOGEN INFORMATION

Immunogen

intercellular adhesion molecule 1

Synonyms

Intercellular adhesion molecule 1,Major group rhinovirus receptor,CD54,ICAM1

Observed MW

90 kDa

APPLICATION

Tested Application

ELISA, WB, IHC, IP, IF, FC

Recommended Dilution

WB: 1:200-1:2000; IP: 1:500-1:5000; IHC: 1:50-1:200; IF: 1:50-1:500

UNIPROT INFORMATION

UniProt ID

P05362

IMAGES

Immunohistochemistry of paraffin-embedded human lung cancer using FNab04100(ICAM-1 antibody) at dilution of 1:50

IP Result of anti-ICAM-1 (IP: FNab04100, 4ug; Detection: FNab04100 1:1000) with Raji cells lysate 1320ug.

L02 cells were subjected to SDS PAGE followed by western blot with FNab04100(ICAM-1 antibody) at dilution of 1:800