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FineTest

SKU:FNab04116

anti- IDE antibody

anti- IDE antibody

Regular price $290.00 USD
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size

anti- IDE antibody

Product Name

IDE antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Plays a role in the cellular breakdown of insulin, IAPP, glucagon, bradykinin, kallidin and other peptides, and thereby plays a role in intercellular peptide signaling. Degrades amyloid formed by APP and IAPP. May play a role in the degradation and clearance of naturally secreted amyloid beta-protein by neurons and microglia. (Microbial infection) The membrane-associated isoform acts as an entry receptor for varicella-zoster virus(VZV).

IMMUNOGEN INFORMATION

Immunogen

insulin-degrading enzyme

Observed MW

100-120 kDa

APPLICATION

Tested Application

ELISA, WB, IHC, IP

Recommended Dilution

WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

P14735

IMAGES

 

Immunohistochemistry of paraffin-embedded human kidney using FNab04116(IDE antibody) at dilution of 1:50
IP Result of anti-IDE (IP:FNab04116, 4ug; Detection:FNab04116 1:500) with HepG2 cells lysate 1600ug.
HepG2 cells were subjected to SDS PAGE followed by western blot with FNab04116(IDE antibody) at dilution of 1:300

 

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