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Immunohistochemistry of paraffin-embedded human pancreas tissue slide using FNab04119(IDH1 Antibody) at dilution of 1:200 -
MCF-7 cells were subjected to SDS PAGE followed by western blot with FNab04119(IDH1 Antibody) at dilution of 1:1000
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SKU:FNab04119
anti- IDH1 antibody
anti- IDH1 antibody
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anti- IDH1 antibody
Product Name
IDH1 antibody
Size
100µg
Form
liquid
Purification
Protein A+G purification
Purity
≥95% as determined by SDS-PAGE
Host
Mouse
Clonality
monoclonal
Isotype
IgG1
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
BACKGROUND
IDH1, also named as PICD and IDP, belongs to the isocitrate and isopropylmalate dehydrogenases family. It is a common feature of a major subset of primary human brain cancers. It can form a homodimer(PMID:15173171).IDH1 mutation is always heterozygotic and IDH1 functions as a dimer, theoretically there will be 25% each wild type and mutant homo-dimers and 50% hetero-dimers present in the tumor cells(PMID:21079649 ).
IMMUNOGEN INFORMATION
Immunogen
isocitrate dehydrogenase 1(NADP+), soluble
Synonyms
IDCD, IDH, IDH1, IDP, IDPC, NADP(+) specific ICDH, Oxalosuccinate decarboxylase, PICD
Observed MW
46kd
APPLICATION
Tested Application
ELISA, WB, IHC, IF
Recommended Dilution
WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:50-1:500
UNIPROT INFORMATION
UniProt ID
IMAGES
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