anti- IL1 Beta antibody

anti- IL1 Beta antibody

Product Name

IL1 Beta antibody

Size

100µg

Form

liquid

Purification

Protein G purified

Purity

≥95% as determined by SDS-PAGE

Host

Mouse

Clonality

monoclonal

Isotype

IgG1

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2.

IMMUNOGEN INFORMATION

Immunogen

interleukin 1, beta

Synonyms

IL1 beta, Catabolin, IL 1, IL 1 beta, IL1 BETA, IL1B, IL1beta, IL1F2, IL-1β, Interleukin 1 beta, interleukin 1, beta

Observed MW

35kDa

APPLICATION

Tested Application

ELISA, IHC, WB

Recommended Dilution

WB: 1:1000-1:4000; IHC: 1:50-1:500

UNIPROT INFORMATION

UniProt ID

P01584

IMAGES