anti- IL11 antibody

anti- IL11 antibody

Product Name

IL11 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Cytokine that stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells and induces megakaryocyte maturation resulting in increased platelet production(PubMed:2145578). Also promotes the proliferation of hepatocytes in response to liver damage. Binding to its receptor formed by IL6ST and either IL11RA1 or IL11RA2 activates a signaling cascade that promotes cell proliferation(PubMed:12919066). Signaling leads to the activation of intracellular protein kinases and the phosphorylation of STAT3.

IMMUNOGEN INFORMATION

Immunogen

interleukin 11

Synonyms

Adipogenesis inhibitory factor, AGIF, IL 11, IL11, interleukin 11, Oprelvekin

Observed MW

25 kDa

APPLICATION

Tested Application

ELISA, WB

Recommended Dilution

WB: 1:200-1:1000

UNIPROT INFORMATION

UniProt ID

P20809

IMAGES