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Immunohistochemistry of paraffin-embedded human tonsillitis tissue slide using FNab04346(Integrin alpha-4 Antibody) at dilution of 1:50 -
Jurkat cells were subjected to SDS PAGE followed by western blot with FNab04346(ITGA4 antibody) at dilution of 1:1000
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SKU:FNab04346
anti- Integrin alpha-4 antibody
anti- Integrin alpha-4 antibody
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anti- Integrin alpha-4 antibody
Product Name
Integrin alpha-4 antibody
Size
100µg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Host
Rabbit
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
BACKGROUND
ITGA4, also named as CD49D, belongs to the integrin alpha chain family. ITGA4 is a receptor for fibronectin, VCAM1 and MADCAM1. ITGA4 recognizes one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. It recognizes the sequence Q-I-D-S in VCAM1. I It recognizes the sequence L-D-T in MADCAM1. On activated endothelial cells ITGA4 triggers homotypic aggregation for most VLA-4-positive leukocyte cell lines. It may also participate in cytolytic T-cell interactions with target cells.
IMMUNOGEN INFORMATION
Immunogen
integrin, alpha 4
Synonyms
CD49D, IA4, Integrin alpha 4, Integrin alpha IV, ITGA4, VLA 4 subunit alpha
Observed MW
140 kDa
APPLICATION
Tested Application
ELISA, WB, IHC
Recommended Dilution
WB: 1500-1:2000; IHC: 1:20-1:200
UNIPROT INFORMATION
UniProt ID
IMAGES
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