anti- KHSRP antibody

anti- KHSRP antibody

Product Name

KHSRP antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Binds to the dendritic targeting element and may play a role in mRNA trafficking(By similarity). Part of a ternary complex that binds to the downstream control sequence(DCS) of the pre-mRNA. Mediates exon inclusion in transcripts that are subject to tissue-specific alternative splicing. May interact with single-stranded DNA from the far-upstream element(FUSE). May activate gene expression. Also involved in degradation of inherently unstable mRNAs that contain AU-rich elements(AREs) in their 3'-UTR, possibly by recruiting degradation machinery to ARE-containing mRNAs.

IMMUNOGEN INFORMATION

Immunogen

KH-type splicing regulatory protein

Synonyms

FBP2, FUBP2, FUSE binding protein 2, KHSRP, KSRP, p75

Observed MW

75 kDa

APPLICATION

Tested Application

ELISA, WB, IHC, IF

Recommended Dilution

WB: 1:500-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

Q92945

IMAGES