anti- KLHL3 antibody

anti- KLHL3 antibody

Product Name

KLHL3 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Substrate-specific adapter of a BCR(BTB-CUL3-RBX1) E3 ubiquitin ligase complex that acts as a regulator of ion transport in the distal nephron. The BCR(KLHL3) complex acts by mediating ubiquitination of WNK4, an inhibitor of potassium channel KCNJ1, leading to WNK4 degradation.

IMMUNOGEN INFORMATION

Immunogen

kelch-like 3(Drosophila)

Synonyms

KIAA1129

Observed MW

65 kDa

APPLICATION

Tested Application

ELISA, WB, IHC, IP

Recommended Dilution

WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

Q9UH77

Immunohistochemistry of paraffin-embedded human liver using FNab04623(KLHL3 antibody) at dilution of 1:100

IP Result of anti-KLHL3 (IP:FNab04623, 4ug; Detection:FNab04623 1:700) with HepG2 cells lysate 2800ug.

HepG2 cells were subjected to SDS PAGE followed by western blot with FNab04623(KLHL3 antibody) at dilution of 1:800