anti- KPNA1 antibody

anti- KPNA1 antibody

Product Name

KPNA1 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

BACKGROUND

The transport of molecules between the nucleus and the cytoplasm in eukaryotic cells is mediated by the nuclear pore complex (NPC), which consists of 60-100 proteins. Small molecules (up to 70 kD) can pass through the nuclear pore by nonselective diffusion while larger molecules are transported by an active process. The protein encoded by this gene belongs to the importin alpha family, and is involved in nuclear protein import. This protein interacts with the recombination activating gene 1 (RAG1) protein and is a putative substrate of the RAG1 ubiquitin ligase. Alternative splicing results in multiple transcript variants.

IMMUNOGEN INFORMATION

Immunogen

karyopherin alpha 1 (importin alpha 5)

Synonyms

RCH2

Observed MW

66 kDa

APPLICATION

Tested Application

ELISA, WB, IHC, IF

Recommended Dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200

UNIPROT INFORMATION

UniProt ID

P52294

IMAGES

Immunohistochemistry of paraffin-embedded human lung cancer using FNab04634(KPNA1 antibody) at dilution of 1:50

Immunofluorescence analysis of U2OS cells using FNab04634(KPNA1 antibody) at dilution of 1:100

K-562 cells were subjected to SDS PAGE followed by western blot with FNab04634(KPNA1 antibody) at dilution of 1:1000