anti- KRAS antibody

anti- KRAS antibody

Product Name

KRAS antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. Plays an important role in the regulation of cell proliferation(PubMed:23698361, PubMed:22711838). Plays a role in promoting oncogenic events by inducing transcriptional silencing of tumor suppressor genes(TSGs) in colorectal cancer(CRC) cells in a ZNF304-dependent manner(PubMed:24623306).

IMMUNOGEN INFORMATION

Immunogen

v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog

Synonyms

C K RAS, c Ki ras, GTPase KRas, K Ras 2, K RAS2A, K RAS2B, K RAS4A, K RAS4B, KI RAS, KRAS, KRAS1, KRAS2, KRAS2B speicifc, Krasa, Krasb, NS3, RASK2

Observed MW

21 kDa

APPLICATION

Tested Application

ELISA, WB, IP, IHC

Recommended Dilution

WB: 1:500 - 1:1000; IHC: 1:50 - 1:200; IP: 1:50 - 1:200

UNIPROT INFORMATION

UniProt ID

P01116

IMAGES

Immunohistochemistry of paraffin-embedded human lung cancer tissue slide using FNab04641(KRAS Antibody) at dilution of 1:100

IP result of anti-KRAS(IP:FNab04641, 4ug; Detection:FNab04641 1:1000) with HeLa cells lysate 2680 ug

mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab04641(KRAS antibody) at dilution of 1:1000