anti- KRT6B antibody

anti- KRT6B antibody

Product Name

KRT6B antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. As many as six of this type II cytokeratin (KRT6) have been identified; the multiplicity of the genes is attributed to successive gene duplication events. The genes are expressed with family members KRT16 and/or KRT17 in the filiform papillae of the tongue, the stratified epithelial lining of oral mucosa and esophagus, the outer root sheath of hair follicles, and the glandular epithelia. Mutations in these genes have been associated with pachyonychia congenita.

IMMUNOGEN INFORMATION

Immunogen

keratin 6B

Synonyms

CK 6B, CK6B, Cytokeratin 6B, K6B, keratin 6B, KRT6B, KRTL1, PC2, Type II keratin Kb10

Observed MW

60 kDa

APPLICATION

Tested Application

ELISA, WB, IHC, IF

Recommended Dilution

WB: 1:1000-1:5000; IHC: 1:50-1:500; IF: 1:200-1:1000

UNIPROT INFORMATION

UniProt ID

P04259

IMAGES

Immunohistochemistry of paraffin-embedded human lung cancer tissue slide using FNab04656(KRT6B Antibody) at dilution of 1:100

Immunofluorescent analysis of U2OS  using FNab04656 (Cytokeratin 6B antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated Goat Anti-Rabbit IgG(H+L)

mouse skin tissue were subjected to SDS PAGE followed by western blot with FNab04656(KRT6B antibody) at dilution of 1:1000