anti- Kv4.2 antibody

anti- Kv4.2 antibody

Product Name

Kv4.2 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shal-related subfamily, members of which form voltage-activated A-type potassium ion channels and are prominent in the repolarization phase of the action potential. This member mediates a rapidly inactivating, A-type outward potassium current which is not under the control of the N terminus as it is in Shaker channels.

IMMUNOGEN INFORMATION

Immunogen

potassium voltage-gated channel, Shal-related subfamily, member 2

Synonyms

KCND2, KIAA1044, Kv4.2, RK5

Observed MW

82kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

UNIPROT INFORMATION

UniProt ID

Q9NZV8

IMAGES

Immunohistochemistry of paraffin-embedded human stomach using FNab04666(Kv4.2 antibody)) at dilution of 1:100

THP-1 cells were subjected to SDS PAGE followed by western blot with FNab04666(Kv4.2 antibody) at dilution of 1:1000