anti- LAS1L antibody

anti- LAS1L antibody

Product Name

LAS1L antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Involved in the biogenesis of the 60S ribosomal subunit. Required for maturation of the 28S rRNA. Functions as a component of the Five Friends of Methylated CHTOP(5FMC) complex; the 5FMC complex is recruited to ZNF148 by methylated CHTOP, leading to desumoylation of ZNF148 and subsequent transactivation of ZNF148 target genes.

IMMUNOGEN INFORMATION

Immunogen

LAS1-like

Observed MW

83 kDa, 70-75 kDa

APPLICATION

Tested Application

ELISA, WB, IP

Recommended Dilution

WB: 1:500-1:2000; IP: 1:200-1:2000

UNIPROT INFORMATION

UniProt ID

Q9Y4W2

IMAGES

IP Result of anti-LAS1L (IP:FNab04703, 4ug; Detection:FNab04703 1:1000) with HEK-293 cells lysate 1200ug.

HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab04703(LAS1L antibody) at dilution of 1:1000