anti- Cleaved LC3 antibody

Cleaved LC3 antibody

Product Name

Cleaved LC3 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

BACKGROUND

MAP1A and MAP1B are microtubule-associated proteins which mediate the physical interactions between microtubules and components of the cytoskeleton. MAP1A and MAP1B each consist of a heavy chain subunit and multiple light chain subunits. The protein encoded by this gene is one of the light chain subunits and can associate with either MAP1A or MAP1B. Two transcript variants encoding different isoforms have been found for this gene. The expression of variant 1 is suppressed in many tumor cell lines, suggesting that may be involved in carcinogenesis.

IMMUNOGEN INFORMATION

Immunogen

microtubule-associated protein 1 light chain 3 alpha

Synonyms

LC3, LC3A, LC3A/B, MAP1A/MAP1B LC3 A, MAP1A/MAP1B light chain 3 A, MAP1ALC3, MAP1BLC3, MAP1LC3A

Observed MW

Refer to Figures

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

UNIPROT INFORMATION

UniProt ID

Q9H492

IMAGES

Immunohistochemistry of paraffin-embedded human breast cancer tissue slide using FNab04716( LC3 antibody) at dilution of 1:200

Chloroquine treated HeLa cells were subjected to SDS PAGE followed by western blot with FNab04716 (LC3 Antibody) at dilution of 1:1000