anti- LGI1 antibody

anti- LGI1 antibody

Product Name

LGI1 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Regulates voltage-gated potassium channels assembled from KCNA1, KCNA4 and KCNAB1. It slows down channel inactivation by precluding channel closure mediated by the KCNAB1 subunit. Ligand for ADAM22 that positively regulates synaptic transmission mediated by AMPA-type glutamate receptors(By similarity). Plays a role in suppressing the production of MMP1/3 through the phosphatidylinositol 3-kinase/ERK pathway. May play a role in the control of neuroblastoma cell survival.

IMMUNOGEN INFORMATION

Immunogen

leucine-rich, glioma inactivated 1

Synonyms

EPT

Observed MW

64 kDa, 58 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:500-1:2000; IHC: 1:50-1:200

UNIPROT INFORMATION

UniProt ID

O95970

IMAGES

Immunohistochemistry of paraffin-embedded human breast cancer tissue slide using FNab04760(LGI1 Antibody) at dilution of 1:50

human brain tissue were subjected to SDS PAGE followed by western blot with FNab04760(LGI1 antibody) at dilution of 1:300