anti- liver Arginase antibody

anti- liver Arginase antibody

Product Name

liver Arginase antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Arginase-1(Liver arginase) belongs to the arginase family. ARG1 is a novel immunohistochemical marker of hepatocellular differentiation in fine needle aspiration cytology and a marker of hepatocytes and hepatocellular neoplasms. ARG1 is closely associated with alternative macrophage activation(PMID:12098359) and ARG1 has been shown to protectmotor neurons from trophic factor deprivation and allow sensory neurons to overcome neurite outgrowth inhibition by myelin proteins(PMID: 20071539).It can exsit as a homotrimer(PMID:16141327) and it has 3 isoforms produced by alternative splicing.Defects in ARG1 are the cause of argininemia(ARGIN). Deletion or TNF-mediated restriction of ARG1 unleashes the production of NO by NOS2, which is critical for pathogen control.(PMID:27117406).

IMMUNOGEN INFORMATION

Immunogen

arginase, liver

Synonyms

ARG1, Arginase 1, liver Arginase, Liver type arginase

Observed MW

35 kDa

APPLICATION

Tested Application

ELISA, IHC, IP, IF, FC, WB

Recommended Dilution

WB: 1:1000-1:10000; IP: 1:500-1:1000; IHC: 1:100-1:400; IF: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

P05089

IMAGES

Immunohistochemistry of paraffin-embedded human liver cancer tissue slide using FNab04800(ARG1 Antibody) at dilution of 1:200

Immunofluorescent analysis of HepG2 cells using FNab04800( ARG1 Antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated Goat Anti-Rabbit IgG(H+L)

IP Result of anti-ARG1 (IP:FNab04800, 4ug; Detection:FNab04800 1:700) with mouse liver tissue lysate 5200ug.

mouse liver tissue were subjected to SDS PAGE followed by western blot with FNab04800(ARG1 antibody) at dilution of 1:1000

RELATED PRODUCTS

• ARG1 antibody
• Recombinant Human Liver Arginase
• liver Arginase antibody
• Rat Arg1(Arginase-1) ELISA Kit
• Mouse Arg1(Arginase-1) ELISA Kit

STATEMENT

Manuals on the web are for your reference only, specifications are subject to the delivery manuals.

FEATURED PRODUCT

•