anti- LPCAT1 antibody

anti- LPCAT1 antibody

Product Name

LPCAT1 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Possesses both acyltransferase and acetyltransferase activities(PubMed:16864775, PubMed:21498505). Activity is calcium-independent(By similarity). Mediates the conversion of 1-acyl-sn-glycero-3-phosphocholine(LPC) into phosphatidylcholine(PC)(PubMed:21498505). Displays a clear preference for saturated fatty acyl-CoAs, and 1-myristoyl or 1-palmitoyl LPC as acyl donors and acceptors, respectively(PubMed:16704971). May synthesize phosphatidylcholine in pulmonary surfactant, thereby playing a pivotal role in respiratory physiology(PubMed:16864775). Involved in the regulation of lipid droplet number and size(PubMed:25491198).

IMMUNOGEN INFORMATION

Immunogen

lysophosphatidylcholine acyltransferase 1

Synonyms

AYTL2, PFAAP3

Observed MW

59 kDa

APPLICATION

Tested Application

ELISA, IF, WB, IP, IHC

Recommended Dilution

WB: 1:500-1:2000; IP: 1:200-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

Q8NF37

IMAGES

Immunohistochemistry of paraffin-embedded human colon cancer slide using FNab04825(LPCAT1 Antibody) at dilution of 1:100

IP Result of anti-LPCAT1 (IP:FNab04825, 3ug; Detection:FNab04825 1:4000) with mouse brain tissue lysate 3600ug.

human lung tissue were subjected to SDS PAGE followed by western blot with FNab04825(LPCAT1 antibody) at dilution of 1:4000