anti- LRP5 antibody

anti- LRP5 antibody

Product Name

LRP5 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

BACKGROUND

This gene encodes a transmembrane low-density lipoprotein receptor that binds and internalizes ligands in the process of receptor-mediated endocytosis. This protein also acts as a co-receptor with Frizzled protein family members for transducing signals by Wnt proteins and was originally cloned on the basis of its association with type 1 diabetes mellitus in humans. This protein plays a key role in skeletal homeostasis and many bone density related diseases are caused by mutations in this gene. Mutations in this gene also cause familial exudative vitreoretinopathy. Alternative splicing results in multiple transcript variants.

IMMUNOGEN INFORMATION

Immunogen

low density lipoprotein receptor-related protein 5

Synonyms

LR3, LRP7

Observed MW

180 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

UNIPROT INFORMATION

UniProt ID

O75197

IMAGES

Immunohistochemistry of paraffin-embedded human liver using FNab04848( LRP5 Antibody) at dilution of 1:50

Various lysates were subjected to SDS PAGE followed by western blot with FNab04848( LRP5 Antibody) at dilution of 1:1000

RELATED PRODUCTS

• Mouse Lrp5(Low-density lipoprotein receptor-related protein 5) ELISA Kit
• Human LRP5(Low-density lipoprotein receptor-related protein 5) ELISA Kit

STATEMENT

Manuals on the web are for your reference only, specifications are subject to the delivery manuals.

FEATURED PRODUCT