anti- LRRC8C antibody

anti- LRRC8C antibody

Product Name

LRRC8C antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Non-essential component of the volume-regulated anion channel(VRAC, also named VSOAC channel), an anion channel required to maintain a constant cell volume in response to extracellular or intracellular osmotic changes. The VRAC channel conducts iodide better than chloride and may also conduct organic osmolytes like taurine. Channel activity requires LRRC8A plus at least one other family member(LRRC8B, LRRC8C, LRRC8D or LRRC8E); channel characteristics depend on the precise subunit composition.

IMMUNOGEN INFORMATION

Immunogen

leucine rich repeat containing 8 family, member C

Synonyms

AD158, FAD158

APPLICATION

Tested Application

ELISA, IF, IHC

Recommended Dilution

IHC: 1:20-1:200; IF: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

Q8TDW0

IMAGES

Immunohistochemistry of paraffin-embedded human heart using FNab04861(LRRC8C antibody) at dilution of 1:50