anti- LRSAM1 antibody

anti- LRSAM1 antibody

Product Name

LRSAM1 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

E3 ubiquitin-protein ligase that mediates monoubiquitination of TSG101 at multiple sites, leading to inactivate the ability of TSG101 to sort endocytic(EGF receptors) and exocytic(HIV-1 viral proteins) cargos(PubMed:15256501). Bacterial recognition protein that defends the cytoplasm from invasive pathogens(PubMed:23245322). Localizes to several intracellular bacterial pathogens and generates the bacteria-associated ubiquitin signal leading to autophagy-mediated intracellular bacteria degradation(xenophagy)(PubMed:23245322, PubMed:25484098).

IMMUNOGEN INFORMATION

Immunogen

leucine rich repeat and sterile alpha motif containing 1

Synonyms

TAL

Observed MW

84 kDa

APPLICATION

Tested Application

ELISA, WB, IHC, IF

Recommended Dilution

WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

Q6UWE0

IMAGES

Immunohistochemistry of paraffin-embedded human skeletal muscle slide using FNab04866(LRSAM1 Antibody) at dilution of 1:50

Jurkat cells were subjected to SDS PAGE followed by western blot with FNab04866(LRSAM1 Antibody) at dilution of 1:1000