anti- MAD2L1 antibody

anti- MAD2L1 antibody

Product Name

MAD2L1 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Component of the spindle-assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. Required for the execution of the mitotic checkpoint which monitors the process of kinetochore-spindle attachment and inhibits the activity of the anaphase promoting complex by sequestering CDC20 until all chromosomes are aligned at the metaphase plate.

IMMUNOGEN INFORMATION

Immunogen

MAD2 mitotic arrest deficient-like 1(yeast)

Synonyms

HSMAD2, MAD2, MAD2 like protein 1, MAD2L1

Observed MW

25-30 kDa

APPLICATION

Tested Application

ELISA, WB, IHC, IP

Recommended Dilution

WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

Q13257

IMAGES

Immunohistochemistry of paraffin-embedded human liver cancer using FNab04923(MAD2L1 antibody) at dilution of 1:50

IP Result of anti-MAD2L1 (IP:FNab04923, 3ug; Detection:FNab04923 1:500) with HEK-293 cells lysate 1800ug.

HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab04923(MAD2L1 antibody) at dilution of 1:800