anti- MAGED1 antibody

anti- MAGED1 antibody

Product Name

MAGED1 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Involved in the apoptotic response after nerve growth factor(NGF) binding in neuronal cells. Inhibits cell cycle progression, and facilitates NGFR-mediated apoptosis. May act as a regulator of the function of DLX family members. May enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme(E2) at the E3:substrate complex. Plays a role in the circadian rythm regulation. May act as RORA co-regulator, modulating the expression of core clock genes such as ARNTL/BMAL1 and NFIL3, induced, or NR1D1, repressed.

IMMUNOGEN INFORMATION

Immunogen

melanoma antigen family D, 1

Synonyms

NRAGE

Observed MW

100 kDa

APPLICATION

Tested Application

ELISA, WB, IHC, IF

Recommended Dilution

WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

Q9Y5V3

IMAGES

Immunohistochemistry of paraffin-embedded human placenta using FNab04947(MAGED1 antibody) at dilution of 1:50

A549 cells were subjected to SDS PAGE followed by western blot with FNab04947(MAGED1 Antibody) at dilution of 1:1000