anti- MARCKSL1 antibody

anti- MARCKSL1 antibody

Product Name

MARCKSL1 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Controls cell movement by regulating actin cytoskeleton homeostasis and filopodium and lamellipodium formation. When unphosphorylated, induces cell migration. When phosphorylated by MAPK8, induces actin bundles formation and stabilization, thereby reducing actin plasticity, hence restricting cell movement, including neuronal migration. May also affect cancer cell migration. May be involved in coupling the protein kinase C and calmodulin signal transduction systems(By similarity).

IMMUNOGEN INFORMATION

Immunogen

MARCKS-like 1

Synonyms

MLP, MRP

Observed MW

40-50kd

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:500-1:2000; IHC: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

P49006

IMAGES

Immunohistochemistry of paraffin-embedded human lung cancer using FNab05010(MARCKSL1 antibody) at dilution of 1:50

Various lysates were subjected to SDS PAGE followed by western blot with FNab05010(Marcksl1 antibody) at dilution of 1:500