anti- Mast Cell Chymase antibody

anti- Mast Cell Chymase antibody

Product Name

Mast Cell Chymase antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Mast Cell Chymase, also named as CYH, CYM and CMA1, belongs to the peptidase S1 family and Granzyme subfamily. It is the major secreted protease of mast cells with suspected roles in vasoactive peptide generation, extracellular matrix degradation, and regulation of gland secretion. CMA1 maybe a target for cardiovascular disease therapies.

IMMUNOGEN INFORMATION

Immunogen

chymase 1, mast cell

Synonyms

Alpha chymase, chymase, chymase 1, mast cell, CMA1, CYH, CYM, Mast Cell Chymase, Mast cell protease I, Mcpt 5, Mcpt5, MCT1

Observed MW

27-30 kDa

APPLICATION

Tested Application

ELISA, WB, IP

Recommended Dilution

WB: 1:200-1:2000; IP: 1:200-1:1000

UNIPROT INFORMATION

UniProt ID

P23946

IMAGES

IP Result of anti-CMA1 (IP: FNab05023, 4ug; Detection: FNab05023 1:300) with mouse heart tissue lysate 2400ug.

mouse heart tissue were subjected to SDS PAGE followed by western blot with FNab05023(CMA1 antibody) at dilution of 1:500