anti- MBD3 antibody

anti- MBD3 antibody

Product Name

MBD3 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Acts as transcriptional repressor and plays a role in gene silencing. Does not bind to DNA by itself(PubMed:12124384). Binds to DNA with a preference for sites containing methylated CpG dinucleotides(in vitro). Binds to a lesser degree DNA containing unmethylated CpG dinucleotides(PubMed:24307175). Recruits histone deacetylases and DNA methyltransferases.

IMMUNOGEN INFORMATION

Immunogen

methyl-CpG binding domain protein 3

Observed MW

33 kDa

APPLICATION

Tested Application

ELISA, WB, IHC, IF, IP

Recommended Dilution

WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

O95983

IMAGES

Immunohistochemistry of paraffin-embedded human endometrial cancer using FNab05035(MBD3 antibody) at dilution of 1:100

IP Result of anti-MBD3 (IP:FNab05035, 4ug; Detection:FNab05035 1:800) with mouse testis tissue lysate 4000ug.

Y79 cells were subjected to SDS PAGE followed by western blot with FNab05035(MBD3 antibody) at dilution of 1:600

RELATED PRODUCTS

• Recombinant Human MBD3
• Human MBD3(Methyl-CpG-binding domain protein 3) ELISA Kit

STATEMENT

Manuals on the web are for your reference only, specifications are subject to the delivery manuals.

FEATURED PRODUCT