anti- MEF2A antibody

anti- MEF2A antibody

Product Name

MEF2A antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Transcriptional activator which binds specifically to the MEF2 element, 5'-YTA[AT](4)TAR-3', found in numerous muscle-specific genes. Also involved in the activation of numerous growth factor-and stress-induced genes. Mediates cellular functions not only in skeletal and cardiac muscle development, but also in neuronal differentiation and survival. Plays diverse roles in the control of cell growth, survival and apoptosis via p38 MAPK signaling in muscle-specific and/or growth factor-related transcription. In cerebellar granule neurons, phosphorylated and sumoylated MEF2A represses transcription of NUR77 promoting synaptic differentiation. Associates with chromatin to the ZNF16 promoter.

IMMUNOGEN INFORMATION

Immunogen

myocyte enhancer factor 2A

Synonyms

ADCAD1, mef2, RSRFC4, RSRFC9

Observed MW

54kd

APPLICATION

Tested Application

ELISA, WB

Recommended Dilution

WB: 1:500 - 1:2000

UNIPROT INFORMATION

UniProt ID

Q02078

IMAGES

various samples were subjected to SDS PAGE followed by western blot with FNab05100(MEF2A antibody) at dilution of 1:1000