anti- MEX3C antibody

anti- MEX3C antibody

Product Name

MEX3C antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

E3 ubiquitin ligase responsible for the post-transcriptional regulation of common HLA-A allotypes. Binds to the 3' UTR of HLA-A2 mRNA, and regulates its levels by promoting mRNA decay. RNA binding is sufficient to prevent translation, but ubiquitin ligase activity is required for mRNA degradation.

IMMUNOGEN INFORMATION

Immunogen

mex-3 homolog C(C. elegans)

Synonyms

RKHD2, RNF194

Observed MW

69 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:500-1:2000; IHC: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

Q5U5Q3

IMAGES

Immunohistochemistry of paraffin-embedded human testis tissue slide using FNab05145(MEX3C Antibody) at dilution of 1:50

HeLa cells were subjected to SDS PAGE followed by western blot with FNab05145(MEX3C antibody) at dilution of 1:1000