anti- MGP antibody

anti- MGP antibody

Product Name

MGP antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

BACKGROUND

This gene encodes a member of the osteocalcin/matrix Gla family of proteins. The encoded vitamin K-dependent protein is secreted by chondrocytes and vascular smooth muscle cells, and functions as a physiological inhibitor of ectopic tissue calcification. Carboxylation status of the encoded protein is associated with calcification of the vasculature in human patients with cardiovascular disease and calcification of the synovial membranes in osteoarthritis patients. Mutations in this gene cause Keutel syndrome in human patients, which is characterized by abnormal cartilage calcification, peripheral pulmonary stenosis and facial hypoplasia.

IMMUNOGEN INFORMATION

Immunogen

matrix Gla protein

Synonyms

GIG36, matrix Gla protein, MGLAP, MGP, NTI

Observed MW

12 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:500 - 1:2000; IHC: 1:100 - 1:200

UNIPROT INFORMATION

UniProt ID

P08493

IMAGES

Immunohistochemistry of paraffin-embedded human breast cancer tissue slide using FNab05170( MGP antibody) at dilution of 1:200

MCF7 cells were subjected to SDS PAGE followed by western blot with FNab05170(MGP antibody) at dilution of 1:1000