anti- MIA3 antibody

anti- MIA3 antibody

Product Name

MIA3 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Plays a role in the transport of cargos that are too large to fit into COPII-coated vesicles and require specific mechanisms to be incorporated into membrane-bound carriers and exported from the endoplasmic reticulum. This protein is required for collagen VII(COL7A1) secretion by loading COL7A1 into transport carriers. It may participate in cargo loading of COL7A1 at endoplasmic reticulum exit sites by binding to COPII coat subunits Sec23/24 and guiding SH3-bound COL7A1 into a growing carrier. Does not play a role in global protein secretion and is apparently specific to COL7A1 cargo loading. However, it may participate in secretion of other proteins in cells that do not secrete COL7A1. It is also specifically required for the secretion of lipoproteins by participating in their export from the endoplasmic reticulum(PubMed:27138255).

IMMUNOGEN INFORMATION

Immunogen

melanoma inhibitory activity family, member 3

Synonyms

KIAA0268, TANGO, TANGO1

Observed MW

250 kDa

APPLICATION

Tested Application

ELISA, IP, WB

Recommended Dilution

WB: 1:500-1:2000; IP: 1:200-1:1000

UNIPROT INFORMATION

UniProt ID

Q5JRA6

IMAGES

IP Result of anti-MIA3 (IP:FNab05174, 5ug; Detection:FNab05174 1:1000) with HeLa cells lysate 3000ug.

HEK-293T cells were subjected to SDS PAGE followed by western blot with FNab05174(MIA3 antibody) at dilution of 1:500

STATEMENT

Manuals on the web are for your reference only, specifications are subject to the delivery manuals.

FEATURED PRODUCT