anti- MICAL1 antibody

anti- MICAL1 antibody

Product Name

MICAL1 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Monooxygenase that promotes depolymerization of F-actin by mediating oxidation of specific methionine residues on actin. Acts by modifying actin subunits through the addition of oxygen to form methionine-sulfoxide, leading to promote actin filament severing and prevent repolymerization(Probable). Acts as a cytoskeletal regulator that connects NEDD9 to intermediate filaments. Also acts as a negative regulator of apoptosis via its interaction with STK38 and STK38L; acts by antagonizing STK38 and STK38L activation by MST1/STK4.

IMMUNOGEN INFORMATION

Immunogen

microtubule associated monoxygenase, calponin and LIM domain containing 1

Synonyms

MICAL, MICAL 1, MICAL1, NICAL

Observed MW

120 kDa

APPLICATION

Tested Application

ELISA, WB, IHC, IP, FC

Recommended Dilution

WB: 1:1000-1:4000; IP: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:50-1:500

UNIPROT INFORMATION

UniProt ID

Q8TDZ2

IMAGES

Immunohistochemistry of paraffin-embedded human lung using FNab05177(MICAL1 antibody) at dilution of 1:100

Immunofluorescent analysis of ( -20°C Ethanol) fixed HeLa cells using FNab05177 (MICAL1 antibody) at dilution of 1:50 and Alexa Fluor 488-Conjugated Goat Anti-Rabbit IgG(H+L)

IP result of anti-MICAL1(IP: FNab05177, 5ug; Detection: FNab05177 1:1000) with Hela cells lysate 2000 ug

Jurkat cells were subjected to SDS PAGE followed by western blot with FNab05177(MICAL1 antibody) at dilution of 1:1000