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SKU:FNab05198

anti- MITF antibody

anti- MITF antibody

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size

anti- MITF antibody

Product Name

MITF antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Transcription factor that regulates the expression of genes with essential roles in cell differentiation, proliferation and survival. Binds to symmetrical DNA sequences(E-boxes)(5'-CACGTG-3') found in the promoters of target genes, such as BCL2 and tyrosinase(TYR). Plays an important role in melanocyte development by regulating the expression of tyrosinase(TYR) and tyrosinase-related protein 1(TYRP1). Plays a critical role in the differentiation of various cell types, such as neural crest-derived melanocytes, mast cells, osteoclasts and optic cup-derived retinal pigment epithelium.

IMMUNOGEN INFORMATION

Immunogen

microphthalmia-associated transcription factor

Synonyms

bHLHe32, MI, MITF, WS2A

Observed MW

60-65kd

APPLICATION

Tested Application

ELISA, WB, FC, IP

Recommended Dilution

WB: 1:500-1:2000; IP: 1:500-1:2000

UNIPROT INFORMATION

UniProt ID

O75030

IMAGES

IP Result of anti-MITF (IP: FNab05198, 4ug; Detection: FNab05198 1:1000) with mouse heart tissue lysate 4000ug.

Jurkat cells were subjected to SDS PAGE followed by western blot with FNab05198(MITF antibody) at dilution of 1:400

RELATED PRODUCTS

STATEMENT

Manuals on the web are for your reference only, specifications are subject to the delivery manuals.

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