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FineTest

SKU:FNab05233

anti- MMP1 antibody

anti- MMP1 antibody

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size

anti- MMP1 antibody

Product Name

MMP1 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

BACKGROUND

This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This secreted protease breaks down the interstitial collagens, including types I, II, and III. The gene is part of a cluster of MMP genes on chromosome 11. Mutations in this gene are associated with chronic obstructive pulmonary disease (COPD). Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.

IMMUNOGEN INFORMATION

Immunogen

matrix metallopeptidase 1 (interstitial collagenase)

Synonyms

CLG, CLGN, Fibroblast collagenase, Interstitial collagenase, Matrix metalloproteinase 1, MMP 1, MMP1

Observed MW

54 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

UNIPROT INFORMATION

UniProt ID

P03956

IMAGES

Immunohistochemistry of paraffin-embedded human cervical cancer tissue slide using FNab05233( MMP1 Antibody) at dilution of 1:200

A549 cells were subjected to SDS PAGE followed by western blot with FNab05233(MMP1 antibody) at dilution of 1:1000

RELATED PRODUCTS

STATEMENT

Manuals on the web are for your reference only, specifications are subject to the delivery manuals.

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