anti- MMP13 antibody

anti- MMP13 antibody

Product Name

MMP13 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Plays a role in the degradation of extracellular matrix proteins including fibrillar collagen, fibronectin, TNC and ACAN. Cleaves triple helical collagens, including type I, type II and type III collagen, but has the highest activity with soluble type II collagen. Can also degrade collagen type IV, type XIV and type X. May also function by activating or degrading key regulatory proteins, such as TGFB1 and CTGF. Plays a role in wound healing, tissue remodeling, cartilage degradation, bone development, bone mineralization and ossification. Plays a role in keratinocyte migration during wound healing. May play a role in cell migration and in tumor cell invasion.It can detect the glycosylated proMMP-13(70 kDa), unglycosylated proform(54 kDa).

IMMUNOGEN INFORMATION

Immunogen

matrix metallopeptidase 13(collagenase 3)

Synonyms

CLG3, Collagenase 3, Matrix metalloproteinase 13, MMP 13, MMP13

Observed MW

54kd,70kd

APPLICATION

Tested Application

ELISA, IHC, WB, IF

Recommended Dilution

WB: 1:500-1:1000; IHC: 1:20-1:200; IF: 1:10-1:100

UNIPROT INFORMATION

UniProt ID

P45452

IMAGES

Immunohistochemistry of paraffin-embedded human breast cancer using FNab05235(MMP13 antibody) at dilution of 1:50

MCF7 cells were subjected to SDS PAGE followed by western blot with FNab05235(MMP13 Antibody) at dilution of 1:600

RELATED PRODUCTS

• Recombinant Human MMP13
• Recombinant Human MMP13
• Human MMP13(Matrix Metalloproteinase 13) ELISA Kit
• Bovine MMP13(Matrix Metalloproteinase 13) ELISA Kit

STATEMENT

Manuals on the web are for your reference only, specifications are subject to the delivery manuals.

FEATURED PRODUCT