anti- MUC16,CA125 antibody

anti- MUC16,CA125 antibody

Product Name

MUC16,CA125 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

MUC16, also named as CA125, is thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces. It is a serum marker that is used routinely in gynecologic practice to monitor patients with ovarian cancer. Most biochemical studies have concluded that MUC16 is a high molecular mass glycoprotein, although estimates of its size range from 200 to 2000 kDa with smaller “subunits” being described by some investigators. The antibody recognizes the C-term of MUC16.

IMMUNOGEN INFORMATION

Immunogen

mucin 16, cell surface associated

Synonyms

CA 125, CA125, FLJ14303, MUC 16, MUC16, Mucin 16

Observed MW

90-100 kDa

APPLICATION

Tested Application

ELISA, WB, IP,IHC

Recommended Dilution

WB: 1:200-1:2000; IP: 1:200-1:2000; IHC: 1:50-1:500

UNIPROT INFORMATION

UniProt ID

Q8WXI7

IMAGES

Immunohistochemistry of paraffin-embedded human ovary tumor tissue slide using FNab05429(MUC16,CA125 Antibody) at dilution of 1:200

IP Result of anti-MUC16,CA125 (IP:FNab05429, 4ug; Detection:FNab05429 1:600) with HeLa cells lysate 1200ug.

HeLa cells were subjected to SDS PAGE followed by western blot with FNab05429(MUC16,CA125 antibody) at dilution of 1:500