anti- MZB1 antibody

anti- MZB1 antibody

Product Name

MZB1 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Associates with immunoglobulin M(IgM) heavy and light chains and promotes IgM assembly and secretion. May exert its effect by acting as a molecular chaperone or as an oxidoreductase as it displays a low level of oxidoreductase activity(By similarity). Isoform 2 may be involved in regulation of apoptosis. Helps to diversify peripheral B-cell functions by regulating Ca(2+) stores, antibody secretion and integrin activation. Acts as a hormone-regulated adipokine/proinflammatory cytokine that is implicated in causing chronic inflammation, affecting cellular expansion and blunting insulin response in adipocytes. May have a role in the onset of insulin resistance.

IMMUNOGEN INFORMATION

Immunogen

hypothetical protein MGC29506

Synonyms

hypothetical protein MGC29506, MZB1, PACAP, pERp1

Observed MW

21 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:500-1:2000; IHC: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

Q8WU39

IMAGES

Immunohistochemistry of paraffin-embedded human gliomas using FNab05530(MZB1 antibody) at dilution of 1:50

Raji cells were subjected to SDS PAGE followed by western blot with FNab05530(MZB1 antibody) at dilution of 1:1000