anti- NDUFS7 antibody

PRODUCT INFORMATION

Product Name

NDUFS7 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

BACKGROUND

This gene encodes a protein that is a subunit of one of the complexes that forms the mitochondrial respiratory chain. This protein is one of over 40 subunits found in complex I, the nicotinamide adenine dinucleotide (NADH):ubiquinone oxidoreductase. This complex functions in the transfer of electrons from NADH to the respiratory chain, and ubiquinone is believed to be the immediate electron acceptor for the enzyme. Mutations in this gene cause Leigh syndrome due to mitochondrial complex I deficiency, a severe neurological disorder that results in bilaterally symmetrical necrotic lesions in subcortical brain regions.

IMMUNOGEN INFORMATION

Immunogen

NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase)

Synonyms

CI-20

Observed MW

24 kDa

APPLICATION

Tested Application

ELISA, WB, IHC, IF

Recommended Dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:100; IF: 1:50 - 1:100

UNIPROT INFORMATION

UniProt ID

O75251

IMAGES

Immunofluorescent analysis of Hela cells, using FNab05634(NDUFS7 antibody) at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).

human brain tissue were subjected to SDS PAGE followed by western blot with FNab05634(NDUFS7 antibody) at dilution of 1:1000