anti- NELFB antibody

PRODUCT INFORMATION

Product Name

NELFB antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Essential component of the NELF complex, a complex that negatively regulates the elongation of transcription by RNA polymerase II. The NELF complex, which acts via an association with the DSIF complex and causes transcriptional pausing, is counteracted by the P-TEFb kinase complex. May be able to induce chromatin unfolding.

IMMUNOGEN INFORMATION

Immunogen

cofactor of BRCA1

Synonyms

COBRA1, KIAA1182

Observed MW

66 kDa

APPLICATION

Tested Application

ELISA, WB, IP, IF

Recommended Dilution

WB: 1:500-1:2000; IP: 1:500-1:1000; IF: 1:10-1:100

UNIPROT INFORMATION

UniProt ID

Q8WX92

IMAGES

BxPC-3 cells were subjected to SDS PAGE followed by western blot with FNab05657( NELFB antibody） at dilution of 1:1000