anti- NGB antibody

PRODUCT INFORMATION

Product Name

NGB antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Involved in oxygen transport in the brain. Hexacoordinate globin, displaying competitive binding of oxygen or the distal His residue to the iron atom. Not capable of penetrating cell membranes. The deoxygenated form exhibits nitrite reductase activity inhibiting cellular respiration via NO-binding to cytochrome c oxidase. Involved in neuroprotection during oxidative stress. May exert its anti-apoptotic activity by acting to reset the trigger level of mitochondrial cytochrome c release necessary to commit the cells to apoptosis.

IMMUNOGEN INFORMATION

Immunogen

neuroglobin

Synonyms

NGB, neuroglobin

Observed MW

16kd

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:500-1:5000; IHC: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

Q9NPG2

IMAGES

human brain tissue were subjected to SDS PAGE followed by western blot with FNab05718(NGB antibody) at dilution of 1:500