anti- NOX4 antibody

PRODUCT INFORMATION

Product Name

NOX4 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Constitutive NADPH oxidase which generates superoxide intracellularly upon formation of a complex with CYBA/p22phox. Regulates signaling cascades probably through phosphatases inhibition. May function as an oxygen sensor regulating the KCNK3/TASK-1 potassium channel and HIF1A activity. May regulate insulin signaling cascade. May play a role in apoptosis, bone resorption and lipolysaccharide-mediated activation of NFKB. May produce superoxide in the nucleus and play a role in regulating gene expression upon cell stimulation.

IMMUNOGEN INFORMATION

Immunogen

NADPH oxidase 4

Synonyms

Kidney oxidase 1, KOX, KOX 1, NADPH oxidase 4, NOX4, Renal NAD(P)H oxidase, RENOX

Observed MW

60 kDa

APPLICATION

Tested Application

ELISA, WB, IHC, IP, IF, FC

Recommended Dilution

WB: 1:200-1:2000; IP: 1:500-1:2000; IHC: 1:100-1:400; IF: 1:10-1:100

UNIPROT INFORMATION

UniProt ID

Q9NPH5

IMAGES

IP Result of anti-NOX4 (IP:FNab05806, 3ug; Detection:FNab05806 1:1000) with HEK-293 cells lysate 1700ug.