anti- NPHP3 antibody

PRODUCT INFORMATION

Product Name

NPHP3 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Required for normal ciliary development and function. Inhibits disheveled-1-induced canonical Wnt-signaling activity and may also play a role in the control of non-canonical Wnt signaling which regulates planar cell polarity. Probably acts as a molecular switch between different Wnt signaling pathways. Required for proper convergent extension cell movements.

IMMUNOGEN INFORMATION

Immunogen

nephronophthisis 3(adolescent)

Synonyms

KIAA2000

Observed MW

145-151 kDa

APPLICATION

Tested Application

ELISA, WB, IF, IHC, IP

Recommended Dilution

WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

Q7Z494

IMAGES

IP Result of anti-NPHP3 (IP:FNab05816, 4ug; Detection:FNab05816 1:1000) with mouse testis tissue lysate 4000ug.