anti- NR3C2 antibody

PRODUCT INFORMATION

Product Name

NR3C2 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Receptor for both mineralocorticoids(MC) such as aldosterone and glucocorticoids(GC) such as corticosterone or cortisol. Binds to mineralocorticoid response elements(MRE) and transactivates target genes. The effect of MC is to increase ion and water transport and thus raise extracellular fluid volume and blood pressure and lower potassium levels.

IMMUNOGEN INFORMATION

Immunogen

nuclear receptor subfamily 3, group C, member 2

Synonyms

MCR, Mineralocorticoid receptor, MLR, MR, NR3C2

Observed MW

107 kDa

APPLICATION

Tested Application

ELISA, WB, IHC, IF, IP

Recommended Dilution

WB: 1:500-1:2000; IP: 1:500-1:1000 ; IHC: 1:20-1:200; IF: 1:10-1:100

UNIPROT INFORMATION

UniProt ID

P08235

IMAGES

Immunofluorescent analysis of HepG2 cells, using NR3C2 antibody FNab05846 at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).

IP Result of anti-NR3C2 (IP:FNab05846, 4ug; Detection:FNab05846 1:500) with HEK-293 cells lysate 3200ug.