anti- NSUN2 antibody

PRODUCT INFORMATION

Product Name

NSUN2 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

RNA methyltransferase that methylates tRNAs, and possibly RNA polymerase III transcripts. Methylates cytosine to 5-methylcytosine(m5C) at positions 34 and 48 of intron-containing tRNA(Leu)(CAA) precursors, and at positions 48, 49 and 50 of tRNA(Gly)(GCC) precursors. May act downstream of Myc to regulate epidermal cell growth and proliferation. Required for proper spindle assembly and chromosome segregation, independently of its methyltransferase activity.

IMMUNOGEN INFORMATION

Immunogen

NOL1/NOP2/Sun domain family, member 2

Synonyms

SAKI, TRM4

Observed MW

90-100 kDa

APPLICATION

Tested Application

ELISA, WB, IHC, IF

Recommended Dilution

WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

Q08J23

IMAGES

Immunofluorescent analysis of Hela cells using FNab05870 (NSUN2 antibody) at dilution of 1:25

HepG2 cells cells were subjected to SDS PAGE followed by western blot with FNab05870(NSUN2 antibody) at dilution of 1:5000