anti- NUDT21 antibody

PRODUCT INFORMATION

Product Name

NUDT21 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Component of the cleavage factor Im(CFIm) complex that plays a key role in pre-mRNA 3'-processing. Involved in association with CPSF6 or CPSF7 in pre-MRNA 3'-end poly(A) site cleavage and poly(A) addition. NUDT21/CPSF5 binds to cleavage and polyadenylation RNA substrates. The homodimer mediates simultaneous sequence-specific recognition of two 5'-UGUA-3' elements within the pre-mRNA. Binds to, but does not hydrolyze mono-and di-adenosine nucleotides. May have a role in mRNA export.

IMMUNOGEN INFORMATION

Immunogen

nudix(nucleoside diphosphate linked moiety X)-type motif 21

Synonyms

CFIM25, CPSF25, CPSF5

Observed MW

26 kDa

APPLICATION

Tested Application

ELISA, WB, IHC, IF, IP

Recommended Dilution

WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

O43809

IMAGES

IP Result of anti-NUDT21 (IP:FNab05904, 3ug; Detection:FNab05904 1:500) with HeLa cells lysate 3000ug.

human brain tissue were subjected to SDS PAGE followed by western blot with FNab05904(NUDT21 antibody) at dilution of 1:500