anti- ORAI1 antibody

PRODUCT INFORMATION

Product Name

ORAI1 antibody

Size

100µg

Form

liquid

Purification

Protein A+G purification

Purity

≥95% as determined by SDS-PAGE

Host

Mouse

Clonality

monoclonal

Isotype

IgG1

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Ca(2+) release-activated Ca(2+)(CRAC) channel subunit which mediates Ca(2+) influx following depletion of intracellular Ca(2+) stores and channel activation by the Ca(2+) sensor, STIM1. CRAC channels are the main pathway for Ca(2+) influx in T-cells and promote the immune response to pathogens by activating the transcription factor NFAT(PubMed:16582901).

IMMUNOGEN INFORMATION

Immunogen

ORAI calcium release-activated calcium modulator 1

Synonyms

CRACM1, FLJ14466, ORAI1, ORAI1 L1, ORAI1 L2, Orail L2, ORAT1, Protein orai 1, TMEM142A, Transmembrane protein 142A

Observed MW

32 kDa

APPLICATION

Tested Application

ELISA, WB,IHC

Recommended Dilution

WB: 1:500-1:2000; IHC: 1:50-1:500

UNIPROT INFORMATION

UniProt ID

Q96D31

HL-60 cells were subjected to SDS PAGE followed by western blot with FNab06002(ORAI1 Antibody) at dilution of 1:1000