anti- P62/SQSTM1 antibody

PRODUCT INFORMATION

Product Name

P62/SQSTM1 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

BACKGROUND

This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone.

IMMUNOGEN INFORMATION

Immunogen

sequestosome 1

Synonyms

P62, sequestosome 1, SQSTM1, Ubiquitin binding protein p62

Observed MW

65 kDa

APPLICATION

Tested Application

ELISA, WB, IHC, IF

Recommended Dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:100; IF: 1:20 - 1:100

UNIPROT INFORMATION

UniProt ID

Q13501

Immunohistochemistry of paraffin-embedded human liver cancer tissue slide using FNab06086( P62 SQSTM1 Antibody) at dilution of 1:50

HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab06086(SQSTM1 antibody) at dilution of 1:1000